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Structure of 902131-33-3
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2-(1H-indazol-4-yl)acetic acid features a rigid indazole core linked via a methylene bridge to a carboxylic acid group, enabling integration into bioactive scaffolds. The electron-rich indazole moiety enhances π-stacking interactions, while the acidic proton supports derivatization and salt formation. This compound exhibits bench-stable handling and compatibility with standard synthetic protocols.
2-(1H-indazol-4-yl)acetic acid serves as a versatile building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its carboxylic acid functionality enables direct amidation, esterification, and coupling reactions under standard conditions. The indazolyl moiety provides a rigid, electron-deficient scaffold with proven utility in kinase inhibitor design. Bench-stable and readily purified by recrystallization, it functions efficiently in solid-phase and solution-phase peptide coupling workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302+H312+H332
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501
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Lot numbers can be found on the outside label of a product: