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CS-W001157 4
Total: USD 88.00

Rebamipide impurity 1

  • CAS No. 90098-05-8

  • Cat. No. CS-B1648
  • Purity≥95%
  • MDL No.MFCD30748222

*For research and further manufacturing use only, not for direct human use.

Rebamipide impurity 1|CS-B1648

Structure of 90098-05-8

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General Information

  • CAS No. 90098-05-8
  • Cat. No. CS-B1648
  • Purity ≥95%
  • MDL No. MFCD30748222
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₉H₁₅ClN₂O₄
  • Molecular Weight 370.79
  • Synonym(s) None
  • SMILES O=C1C=C(CC(C(O)=O)NC(C2=CC(Cl)=CC=C2)=O)C3=CC=CC=C3N1

Description

This quinoline-based carboxylic acid integrates a chlorobenzoyl amide group, enhancing its utility in medicinal chemistry. The electron-deficient aromatic system supports targeted conjugation, while the dihydro-2-oxo scaffold provides structural rigidity for bioactive molecule design under standard bench conditions.

Application

α-[(3-Chlorobenzoyl)amino]-1,2-dihydro-2-oxo-4-quinolinepropanoic acid serves as a versatile building block in the synthesis of quinoline-based pharmaceutical intermediates. Its structure integrates a chlorinated aromatic amide, a quinoline core, and a propanoic acid moiety, enabling diverse transformations including amidation, esterification, and metal-catalyzed cross-couplings. The compound exhibits good bench stability and facilitates purification via standard chromatographic methods, supporting its use in iterative synthetic sequences for targeted heterocyclic scaffolds.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   99.26
  • LogP   2.6072
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   5

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