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CS-W001157 4
Total: USD 88.00

(4-Bromophenyl)(phenyl)methanone

  • CAS No. 90-90-4

  • Cat. No. CS-W007824
  • Purity≥97%
  • MDL No.MFCD00000103

*For research and further manufacturing use only, not for direct human use.

(4-Bromophenyl)(phenyl)methanone|CS-W007824

Structure of 90-90-4

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General Information

  • CAS No. 90-90-4
  • Cat. No. CS-W007824
  • Purity ≥97%
  • MDL No. MFCD00000103
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₉BrO
  • Molecular Weight 261.11
  • Synonym(s) p-Benzoylbromobenzene
  • SMILES O=C(C1=CC=C(Br)C=C1)C2=CC=CC=C2

Description

(4-Bromophenyl)(phenyl)methanone is a brominated aryl ketone featuring a para-brominated phenyl ring linked to a benzoyl group. This electron-deficient scaffold enables direct functionalization in cross-coupling reactions and serves as a key intermediate in the synthesis of pharmaceuticals and advanced organic materials under standard conditions.

Application

(4-Bromophenyl)(phenyl)methanone serves as a versatile aryl ketone building block for Suzuki-Miyaura cross-coupling and nucleophilic addition reactions. Its bench-stable nature and tolerance to diverse reaction conditions enable efficient construction of biaryl scaffolds and functionalized ketones in medicinal chemistry and materials synthesis workflows.

Synthesis

  • Route1

    References

    • Eshtiagh-Hosseini, Hossein; Tabari, Taymaz; Eshghi, Hossein Asian Journal of Chemistry, 2013 , vol. 25, # 6 p. 3307 - 3312
  • Route2

    References

    • Ishiyama, Tatsuo; Kizaki, Hiroe; Hayashi, Takahiro; Suzuki, Akira; Miyaura, Norio Journal of Organic Chemistry, 1998 , vol. 63, # 14 p. 4726 - 4731
  • Route3
    • In-stock
      (4-Bromophenyl)boronic acid|CS-W008847
      5467-74-3
    • null|null
      98-88-4
    • ~81%
    • In-stock
      (4-Bromophenyl)(phenyl)methanone|CS-W007824
      90-90-4

    References

    • Ogawa, Daisuke; Hyodo, Keita; Suetsugu, Masato; Li, Jing; Inoue, Yoshiaki; Fujisawa, Mamoru; Iwasaki, Masayuki; Takagi, Kentaro; Nishihara, Yasushi Tetrahedron, 2013 , vol. 69, # 12 p. 2565 - 2571

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   3.6801
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   2

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