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CS-W001157 4
Total: USD 88.00

(2-Aminoethyl)triphenylphosphonium bromide

  • CAS No. 89996-00-9

  • Cat. No. CS-0459907
  • Purity≥95%
  • MDL No.MFCD30470356

*For research and further manufacturing use only, not for direct human use.

(2-Aminoethyl)triphenylphosphonium bromide|CS-0459907

Structure of 89996-00-9

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General Information

  • CAS No. 89996-00-9
  • Cat. No. CS-0459907
  • Purity ≥95%
  • MDL No. MFCD30470356
  • Storage RT, sealed storage, away from moisture and light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₀H₂₁BrNP
  • Molecular Weight 386.27
  • Synonym(s) Phosphonium, (2-aminoethyl)triphenyl-, bromide
  • SMILES NCC[P+](C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3.[Br-]

Description

This quaternary phosphonium salt features a positively charged phosphorus center flanked by three phenyl groups and an (2-aminoethyl) side chain. The cationic nature enhances membrane permeability, while the amine functionality enables conjugation or hydrogen bonding in biological applications. Bench-stable and moisture-tolerant, it serves as a versatile building block for targeted delivery systems and functional materials.

Application

(2-Aminoethyl)triphenylphosphonium bromide serves as a versatile quaternary phosphonium salt enabling efficient nucleophilic substitutions and phase-transfer catalysis. Its stable, bench-friendly nature and tolerance to diverse functional groups facilitate reliable synthesis of phosphonium-based reagents and catalysts. Functions as a key building block in the preparation of phosphine ligands and bioactive phosphonium derivatives.

Synthesis

  • Route1
    • In-stock
      2-Bromoethylammonium bromide|CS-W008659
      2576-47-8
    • null|null
      603-35-0
    • ~19%
    • In-stock
      (2-Aminoethyl)triphenylphosphonium bromide|CS-0459907
      89996-00-9

    References

    • Maryanoff,B.E.; Reitz,A.; Duhl-Emswiler,B. Journal of the American Chemical Society, 1985 , vol. 10, p. 217

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   -0.0568
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   5

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