6-Fluoro-1H-pyrrolo[2,3-b]pyridine

Name: 6-Fluoro-1H-pyrrolo[2,3-b]pyridine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 898746-42-4
Cat. No. CS-D0706
Purity≥95%
MDL No.MFCD06659668

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

6-Fluoro-1H-pyrrolo[2,3-b]pyridine|CS-D0706

Structure of 898746-42-4

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 898746-42-4
Cat. No. CS-D0706
Purity ≥95%
MDL No. MFCD06659668
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₅FN₂
Molecular Weight 136.13
Synonym(s) 1H-Pyrrolo[2,3-b]pyridine, 6-fluoro-
SMILES FC1=CC=C2C(NC=C2)=N1

Description

6-Fluoro-1H-pyrrolo[2,3-b]pyridine is a fluorinated heterocyclic scaffold featuring a pyrrolopyridine core with strategic electron-withdrawing fluorination. This bench-stable, moisture-tolerant compound integrates readily into medicinal chemistry libraries, serving as a key building block for kinase inhibitors and CNS-targeted therapeutics.

Application

6-Fluoro-1H-pyrrolo[2,3-b]pyridine serves as a versatile heterocyclic building block in medicinal chemistry, enabling direct functionalization at the C5 position via palladium-catalyzed cross-coupling reactions. Its fluorinated pyrrolopyridine core offers enhanced metabolic stability and modulated electronic properties, while maintaining bench-stable, crystalline characteristics suitable for scalable synthesis and purification.

Synthesis

Route1
- 1001070-28-5
- ~96%
- In-stock
  
  898746-42-4
References
- Stoit, Axel R.; den Hartog, Arnold P.; Mons, Harry; van Schaik, Sjoerd; Barkhuijsen, Nynke; Stroomer, Cees; Coolen, Hein K.A.C.; Reinders, Jan Hendrik; Adolfs, Tiny J.P.; van der Neut, Martina; Keizer, Hiskias; Kruse, Chris G. Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 1 p. 188 - 193
Route2
- In-stock
  
  143468-13-7
- ~%
- In-stock
  
  898746-42-4
References
- Bioorganic and Medicinal Chemistry Letters, , vol. 23, # 23 p. 6396 - 6400

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 28.68
LogP 1.702
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 0

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyrrole compounds

Key Words

6-Fluoro-1H-pyrrolo[2,3-b]pyridine sigma6-Fluoro-1H-pyrrolo[2,3-b]pyridine manufacturer6-Fluoro-1H-pyrrolo[2,3-b]pyridine price6-Fluoro-1H-pyrrolo[2,3-b]pyridine structure6-Fluoro-1H-pyrrolo[2,3-b]pyridine SDSbuy 6-Fluoro-1H-pyrrolo[2,3-b]pyridine6-Fluoro-1H-pyrrolo[2,3-b]pyridine supplier6-Fluoro-1H-pyrrolo[2,3-b]pyridine uses6-Fluoro-1H-pyrrolo[2,3-b]pyridine molecular weightprice of 6-Fluoro-1H-pyrrolo[2,3-b]pyridine6-Fluoro-1H-pyrrolo[2,3-b]pyridine chemical name formula of 6-Fluoro-1H-pyrrolo[2,3-b]pyridine

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

6-Fluoro-1H-pyrrolo[2,3-b]pyridine

CAS No. 898746-42-4

Recommended Products