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CS-W001157 4
Total: USD 88.00

5-Cyclopropyl-1H-imidazole

  • CAS No. 89830-98-8

  • Cat. No. CS-W000144
  • Molecule weightNone
  • Purity≥95%
  • MDL No.MFCD18711516

*For research and further manufacturing use only, not for direct human use.

5-Cyclopropyl-1H-imidazole|CS-W000144

Structure of 89830-98-8

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General Information

  • CAS No. 89830-98-8
  • Cat. No. CS-W000144
  • Purity ≥95%
  • MDL No. MFCD18711516
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₈N₂
  • Molecular Weight None
  • Synonym(s) 4-cyclopropyl-1H-imidazole
  • SMILES C1(C2CC2)=CN=CN1

Description

5-Cyclopropyl-1H-imidazole delivers a sterically modulated imidazole scaffold with enhanced lipophilicity and metabolic stability. This bench-stable heterocycle integrates readily into medicinal chemistry libraries, serving as a bioisostere for phenyl or pyridine rings in target-directed drug discovery.

Application

5-Cyclopropyl-1H-imidazole serves as a versatile heterocyclic building block in medicinal chemistry, offering enhanced metabolic stability and tunable basicity due to the cyclopropyl substituent. It functions as a bioisostere for phenyl or pyridine moieties in drug discovery, enabling improved solubility and membrane permeability. The imidazole core facilitates metal coordination and hydrogen bonding, supporting its use in catalyst design and targeted protein inhibition. Its bench-stable nature and compatibility with standard coupling reactions make it a practical choice for iterative synthesis.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   28.68
  • LogP   1.2871
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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