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Structure of 89830-98-8
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5-Cyclopropyl-1H-imidazole delivers a sterically modulated imidazole scaffold with enhanced lipophilicity and metabolic stability. This bench-stable heterocycle integrates readily into medicinal chemistry libraries, serving as a bioisostere for phenyl or pyridine rings in target-directed drug discovery.
5-Cyclopropyl-1H-imidazole serves as a versatile heterocyclic building block in medicinal chemistry, offering enhanced metabolic stability and tunable basicity due to the cyclopropyl substituent. It functions as a bioisostere for phenyl or pyridine moieties in drug discovery, enabling improved solubility and membrane permeability. The imidazole core facilitates metal coordination and hydrogen bonding, supporting its use in catalyst design and targeted protein inhibition. Its bench-stable nature and compatibility with standard coupling reactions make it a practical choice for iterative synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: