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CS-W001157 4
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(S)-2-((tert-Butoxycarbonyl)amino)-3-cyclopropylpropanoic acid

  • CAS No. 89483-06-7

  • Cat. No. CS-0186158
  • Molecule weight229.27
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(S)-2-((tert-Butoxycarbonyl)amino)-3-cyclopropylpropanoic acid|CS-0186158

Structure of 89483-06-7

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General Information

  • CAS No. 89483-06-7
  • Cat. No. CS-0186158
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₉NO₄
  • Molecular Weight 229.27
  • Synonym(s) (2S)-2-[[(tert-butoxy)carbonyl]amino]-3-cyclopropylpropanoic acid
  • SMILES CC(C)(OC(N[C@H](C(O)=O)CC1CC1)=O)C

Description

(S)-2-((tert-Butoxycarbonyl)amino)-3-cyclopropylpropanoic acid is a chiral amino acid derivative featuring a cyclopropyl group that imparts conformational rigidity and enhanced metabolic stability. The tert-butoxycarbonyl (Boc) protecting group enables safe handling and convenient deprotection during peptide synthesis. This scaffold integrates readily into peptidomimetic architectures, offering structural diversity for drug discovery applications.

Application

(S)-2-((tert-Butoxycarbonyl)amino)-3-cyclopropylpropanoic acid serves as a valuable chiral building block for the synthesis of bioactive peptides and heterocyclic scaffolds. The Boc-protected amine and carboxylic acid functionalities enable straightforward coupling reactions, while the cyclopropyl group imparts conformational rigidity. Bench-stable and compatible with standard peptide synthesis protocols, it facilitates efficient purification and orthogonal functional group manipulation in medicinal chemistry workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   1.7644
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   4

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