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CS-W001157 4
Total: USD 88.00

6-Bromo-3-methylpyridin-2-amine

  • CAS No. 89466-16-0

  • Cat. No. CS-W007289
  • Purity≥98%
  • MDL No.MFCD17014961

*For research and further manufacturing use only, not for direct human use.

6-Bromo-3-methylpyridin-2-amine|CS-W007289

Structure of 89466-16-0

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General Information

  • CAS No. 89466-16-0
  • Cat. No. CS-W007289
  • Purity ≥98%
  • MDL No. MFCD17014961
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇BrN₂
  • Molecular Weight 187.04
  • Synonym(s) 6-BroMo-3-Methyl-2-pyridinaMine
  • SMILES NC1=NC(Br)=CC=C1C

Description

6-Bromo-3-methylpyridin-2-amine features a bromine atom at the 6-position and a methyl group at the 3-position on a pyridine ring bearing an amino functionality at the 2-position. This electron-deficient heterocycle integrates readily into cross-coupling reactions, enabling efficient access to functionalized pyridine scaffolds in medicinal chemistry and materials science.

Application

6-Bromo-3-methylpyridin-2-amine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its bromine substituent. The pyridin-2-amine core provides a handle for further functionalization, while the methyl group enhances metabolic stability. Its bench-stable nature and compatibility with standard synthetic protocols facilitate efficient assembly of heterocyclic scaffolds in API development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   1.73472
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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