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CS-W001157 4
Total: USD 88.00

2-Bromo-3-fluoro-benzaldehyde

  • CAS No. 891180-59-9

  • Cat. No. CS-W004707
  • Purity≥98%
  • MDL No.MFCD07782044

*For research and further manufacturing use only, not for direct human use.

2-Bromo-3-fluoro-benzaldehyde|CS-W004707

Structure of 891180-59-9

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General Information

  • CAS No. 891180-59-9
  • Cat. No. CS-W004707
  • Purity ≥98%
  • MDL No. MFCD07782044
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₄BrFO
  • Molecular Weight 203.01
  • Synonym(s) None
  • SMILES BrC1=C(C=O)C=CC=C1F

Description

2-Bromo-3-fluorobenzaldehyde features a fluorine atom adjacent to a bromine-substituted aromatic ring, enabling selective functionalization in cross-coupling reactions. The aldehyde group provides a reactive handle for nucleophilic additions and condensation chemistry. This electron-deficient aryl aldehyde exhibits enhanced stability under standard conditions and facilitates the synthesis of complex heterocycles and pharmaceutical intermediates.

Application

2-Bromo-3-fluorobenzaldehyde serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling direct incorporation of halogenated aromatic motifs. Its ortho-halogenated benzaldehyde framework facilitates palladium-catalyzed cross-coupling reactions and supports further functionalization via electrophilic substitution or nucleophilic addition. The molecule exhibits good bench stability and is compatible with standard purification techniques, making it well-suited for iterative synthetic sequences and scale-up applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   2.4007
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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