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Structure of 890129-90-5
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3-Cyclopropyl-4-fluoroaniline features a cyclopropyl group at the meta position and a fluorine atom at the para position relative to the amine, delivering enhanced metabolic stability and electron-withdrawing character. This scaffold integrates readily into pharmaceutical intermediates and bioactive molecules, offering improved lipophilicity and targeted binding affinity in medicinal chemistry applications.
3-Cyclopropyl-4-fluoroaniline serves as a valuable building block in medicinal chemistry, enabling the synthesis of fluorinated aromatic scaffolds with enhanced metabolic stability. Its cyclopropyl group imparts favorable lipophilicity and conformational rigidity, while the fluoro substituent supports target binding through polar interactions. The amine functionality facilitates straightforward derivatization via acylation, alkylation, or coupling reactions, and the compound exhibits excellent bench stability and ease of purification, making it well-suited for high-throughput screening campaigns and process-scale applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: