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CS-W001157 4
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4-(Dimethylamino)pyridine-2-carboxylic acid

  • CAS No. 890092-04-3

  • Cat. No. CS-0070548
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-(Dimethylamino)pyridine-2-carboxylic acid|CS-0070548

Structure of 890092-04-3

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General Information

  • CAS No. 890092-04-3
  • Cat. No. CS-0070548
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀N₂O₂
  • Molecular Weight 166.18
  • Synonym(s) 4-(DiMethylaMino)picolinic acid
  • SMILES O=C(O)C1=NC=CC(N(C)C)=C1

Description

This bifunctional pyridine-carboxylic acid integrates a strongly electron-donating dimethylamino group with a reactive carboxylic acid handle, enabling efficient coupling reactions. The ortho-positioned nitrogen and electron-rich pyridine ring enhance nucleophilicity, while the carboxylic acid facilitates conjugation in synthetic workflows.

Application

4-(Dimethylamino)pyridine-2-carboxylic acid serves as a versatile building block in medicinal chemistry and catalysis, combining a pyridine core with both a basic dimethylaminopyridine moiety and a carboxylic acid functional group. Its dual functionality enables participation in amide coupling, metal coordination, and heterocycle formation. The compound exhibits good bench stability and facilitates efficient purification, making it well-suited for use in modular synthesis workflows targeting bioactive scaffolds.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   53.43
  • LogP   0.8458
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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