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CS-W001157 4
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5-(Chlorosulfonyl)-2-methylbenzoic acid

  • CAS No. 89001-57-0

  • Cat. No. CS-W022259
  • Purity≥98%
  • MDL No.MFCD03989642
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-(Chlorosulfonyl)-2-methylbenzoic acid|CS-W022259

Structure of 89001-57-0

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Description

5-(Chlorosulfonyl)-2-methylbenzoic acid features a chlorosulfonyl group flanked by a methyl-substituted aromatic ring and a carboxylic acid handle, enabling direct conjugation in electrophilic functionalization. This bench-stable derivative integrates readily into synthetic pathways requiring sulfonylating agents with orthogonal reactivity.

Application

5-(Chlorosulfonyl)-2-methylbenzoic acid serves as a versatile building block for sulfonamide and sulfonic acid derivatives, enabling efficient functionalization in medicinal chemistry and materials science. Its ortho-methyl group enhances stability and directs electrophilic substitution, while the chlorosulfonyl moiety offers high reactivity toward nucleophiles. The carboxylic acid functionality supports derivatization via esterification or amide coupling, facilitating integration into complex molecular architectures.

General Information

  • CAS No. 89001-57-0
  • Cat. No. CS-W022259
  • Purity ≥98%
  • MDL No. MFCD03989642
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇ClO₄S
  • Molecular Weight 234.66
  • Synonym(s) Benzoic acid, 5-(chlorosulfonyl)-2-methyl- (9CI)
  • SMILES O=C(O)C1=CC(S(=O)(Cl)=O)=CC=C1C

Computational Chemistry Data

  • TPSA   71.44
  • LogP   1.62072
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group :
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

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