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CS-W001157 4
Total: USD 88.00

N-Methyl-D-valine

  • CAS No. 88930-14-7

  • Cat. No. CS-0010220
  • Purity≥97%
  • MDL No.MFCD19216536

*For research and further manufacturing use only, not for direct human use.

N-Methyl-D-valine|CS-0010220

Structure of 88930-14-7

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General Information

  • CAS No. 88930-14-7
  • Cat. No. CS-0010220
  • Purity ≥97%
  • MDL No. MFCD19216536
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₃NO₂
  • Molecular Weight 131.17
  • Synonym(s) None
  • SMILES CC(C)[C@@H](NC)C(O)=O

Description

N-Methyl-D-valine is a sterically hindered, bench-stable D-amino acid derivative featuring a methylated nitrogen and branched aliphatic side chain. This configuration enhances metabolic resistance and conformational rigidity, making it valuable for peptide backbone modification in bioactive molecule design.

Application

N-Methyl-D-valine serves as a valuable chiral building block in peptide synthesis, offering enhanced metabolic stability and conformational rigidity. Its N-methylated amine group improves membrane permeability and resistance to proteolytic degradation, while the D-valine backbone provides stereochemical control for bioactive peptide design. The compound exhibits excellent bench stability and facilitates efficient coupling reactions with minimal racemization, making it well-suited for both academic and industrial applications in medicinal chemistry and drug discovery.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   49.33
  • LogP   0.315
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   3

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