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Structure of 888499-98-7
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5-Cyclopropyl-2-methoxynicotinaldehyde is a bench-stable, electron-deficient aldehyde featuring a cyclopropyl group at the 5-position and a methoxy substituent at the 2-position of the pyridine ring. This combination enhances solubility and modulates reactivity, enabling efficient coupling in transition-metal-catalyzed transformations. The aldehyde moiety serves as a direct handle for C–C bond formation via nucleophilic addition or imine synthesis.
5-Cyclopropyl-2-methoxynicotinaldehyde serves as a versatile building block in medicinal chemistry, enabling efficient access to bioactive heterocycles via condensation and coupling reactions. Its aldehyde functionality exhibits excellent stability and compatibility with diverse functional groups, facilitating straightforward purification and integration into complex molecular architectures. The cyclopropyl and methoxy substituents provide favorable steric and electronic profiles, enhancing metabolic stability and target binding affinity in API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: