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CS-W001157 4
Total: USD 88.00

2-(Bromomethyl)-5-nitropyridine

  • CAS No. 887588-20-7

  • Cat. No. CS-0067085
  • Molecule weight217.02
  • Purity≥97%
  • MDL No.MFCD09029365

*For research and further manufacturing use only, not for direct human use.

2-(Bromomethyl)-5-nitropyridine|CS-0067085

Structure of 887588-20-7

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General Information

  • CAS No. 887588-20-7
  • Cat. No. CS-0067085
  • Purity ≥97%
  • MDL No. MFCD09029365
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅BrN₂O₂
  • Molecular Weight 217.02
  • Synonym(s) 2-BROMOMETHYL-5NITROPYRIDINE
  • SMILES O=[N+](C1=CN=C(CBr)C=C1)[O-]

Description

2-(Bromomethyl)-5-nitropyridine features a bromomethyl group flanked by a nitropyridine core, enabling direct functionalization in cross-coupling and nucleophilic substitution reactions. This electron-deficient heterocycle offers enhanced reactivity under standard conditions, facilitating efficient incorporation into complex molecular architectures.

Application

2-(Bromomethyl)-5-nitropyridine serves as a versatile bifunctional building block for medicinal chemistry and process development. The bromomethyl group enables nucleophilic substitution reactions, while the nitropyridine moiety provides a polar, electron-deficient heterocyclic scaffold. It facilitates efficient coupling with amines, thiols, and other nucleophiles under mild conditions, offering high functional group tolerance and ease of purification. Its bench-stable nature supports reliable handling in multi-step syntheses.

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P280-P301+P330+P331-P304+P340

Quality Control

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Computational Chemistry Data

  • TPSA   56.03
  • LogP   1.8847
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

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