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CS-W001157 4
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tert-Butyl 4,7-diazaspiro[2.5]octane-7-carboxylate

  • CAS No. 886766-28-5

  • Cat. No. CS-B0646
  • Purity≥95%
  • MDL No.MFCD08685931

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 4,7-diazaspiro[2.5]octane-7-carboxylate|CS-B0646

Structure of 886766-28-5

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General Information

  • CAS No. 886766-28-5
  • Cat. No. CS-B0646
  • Purity ≥95%
  • MDL No. MFCD08685931
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₂₀N₂O₂
  • Molecular Weight 212.29
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)N1CC2(CC2)NCC1

Description

tert-Butyl 4,7-diazaspiro[2.5]octane-7-carboxylate features a rigid spirocyclic core with two nitrogen atoms at the 4- and 7-positions, enabling precise spatial control in molecular scaffolds. The tert-butyl ester group enhances solubility and stability during synthetic manipulations. This compound serves as a key building block for bioactive heterocycles, particularly in medicinal chemistry campaigns targeting CNS disorders and kinase inhibitors.

Application

tert-Butyl 4,7-diazaspiro[2.5]octane-7-carboxylate serves as a versatile spirocyclic scaffold for medicinal chemistry and catalytic synthesis. The protected diamine core exhibits excellent bench stability and facilitates efficient functionalization at both nitrogen atoms. It functions as a key building block in the construction of complex heterocycles and bioactive molecules, enabling orthogonal derivatization under standard coupling conditions. Its robust tert-butyl ester group allows for straightforward deprotection and integration into diverse synthetic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   41.57
  • LogP   1.3593
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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