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Structure of 886762-09-0
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3-Chloro-6-(trifluoromethyl)pyridin-2-amine delivers a potent electron-deficient pyridine scaffold with enhanced stability and solubility under standard conditions. This trifluoromethyl-substituted heterocycle integrates readily into medicinal chemistry campaigns, enabling efficient coupling reactions via its primary amine functionality.
3-Chloro-6-(trifluoromethyl)pyridin-2-amine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its reactive chloropyridine moiety. The trifluoromethyl group enhances metabolic stability and lipophilicity, while the pyridin-2-amine functionality provides a handle for further derivatization via amide coupling or metal coordination. Its bench-stable nature and compatibility with diverse reaction conditions make it suitable for scalable synthesis of bioactive heterocycles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P233-P260-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P340-P362-P403-P405-P501
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Lot numbers can be found on the outside label of a product: