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CS-W001157 4
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Fmoc-ε-Acp-OH

  • CAS No. 88574-06-5

  • Cat. No. CS-W009405
  • Purity≥98%
  • MDL No.MFCD00077045

*For research and further manufacturing use only, not for direct human use.

Fmoc-ε-Acp-OH|CS-W009405

Structure of 88574-06-5

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General Information

  • CAS No. 88574-06-5
  • Cat. No. CS-W009405
  • Purity ≥98%
  • MDL No. MFCD00077045
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₁H₂₃NO₄
  • Molecular Weight 353.41
  • Synonym(s) N-Fmoc-6-Aminohexanoic acid
  • SMILES O=C(CCCCCNC(OCC1C2=C(C=CC=C2)C3=C1C=CC=C3)=O)O

Description

Fmoc-ε-Acp-OH is a protected lysine analog featuring a benzyl ether-linked side chain, enabling site-specific incorporation into peptides during solid-phase synthesis. This derivative delivers enhanced solubility and stability under standard coupling conditions, facilitating efficient conjugation in complex peptide architectures.

Synthesis

  • Route1
    • null|null
      28920-43-6
    • In-stock
      6-Aminocaproic acid|CS-2204
      60-32-2
    • ~93%
    • In-stock
      Fmoc-ε-Acp-OH|CS-W009405
      88574-06-5

    References

    • Khandazhinskaya; Kukhanova; Jasko Russian Journal of Bioorganic Chemistry, 2005 , vol. 31, # 4 p. 352 - 356
  • Route2
    • null|null
      102774-86-7
    • In-stock
      6-Aminocaproic acid|CS-2204
      60-32-2
    • ~99%
    • In-stock
      Fmoc-ε-Acp-OH|CS-W009405
      88574-06-5

    References

    • Wojczewski, Christian; Schwarzer, Karin; Engels, Joachim W. Helvetica Chimica Acta, 2000 , vol. 83, # 6 p. 1268 - 1277
  • Route3

    References

    • Wasner, Marita; Suhadolnik, Robert J.; Horvath, Susan E.; Adelson, Martin E.; Kon, Ning; Guan, Ming-Xu; Henderson, Earl E.; Pfleiderer, Wolfgang Helvetica Chimica Acta, 1997 , vol. 80, # 4 p. 1061 - 1072

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   4.1701
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   8

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