Lot numbers can be found on the outside label of a product:
6-Bromo-4-methoxy-1H-indazole
-
CAS No. 885519-21-1
- Cat. No. CS-0041911
- Purity≥98%
- MDL No.MFCD07781361
*For research and further manufacturing use only, not for direct human use.
Structure of 885519-21-1
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 885519-21-1
- Cat. No. CS-0041911
- Purity ≥98%
- MDL No. MFCD07781361
- Storage Store at room temperature
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₈H₇BrN₂O
- Molecular Weight 227.06
- Synonym(s) 6-Bromo-4-methoxyindazole
- SMILES COC1=CC(Br)=CC2=C1C=NN2
Description
6-Bromo-4-methoxy-1H-indazole is a bench-stable heterocyclic building block featuring a bromine atom at the 6-position and a methoxy group at the 4-position, enabling straightforward functionalization via cross-coupling. This electron-deficient indazole scaffold integrates efficiently into pharmaceutical and agrochemical intermediates, offering enhanced solubility and reactivity in transition-metal-catalyzed transformations.
Application
6-Bromo-4-methoxy-1H-indazole serves as a versatile building block for medicinal chemistry and materials science, enabling palladium-catalyzed cross-coupling reactions due to its well-defined halogen reactivity. The methoxy group enhances solubility and modulates electronic properties, while the indazole core provides a stable, heteroaromatic scaffold with proven utility in kinase inhibitor and bioactive molecule development. Bench-stable and amenable to standard purification techniques, it facilitates efficient synthesis of complex molecular architectures.
Synthesis
-
Route1
-
In-stock
537013-51-7 - ~%
-
In-stock
885519-21-1
References
-
Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 23 p. 7100 - 7105
-
-
Route2
-
In-stock
1082040-45-6 - ~%
-
In-stock
885519-21-1
References
-
EP2226315 A1, ; Page/Page column 66-67 ;
-
-
Route3
-
461-96-1 - ~%
-
In-stock
885519-21-1
References
-
Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 23 p. 7100 - 7105
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 37.91
- LogP 2.334
- H_Acceptors 2
- H_Donors 1
- Rotatable_Bonds 1
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 6-Bromo-4-methoxy-1H-indazole sigma6-Bromo-4-methoxy-1H-indazole manufacturer6-Bromo-4-methoxy-1H-indazole price6-Bromo-4-methoxy-1H-indazole structure6-Bromo-4-methoxy-1H-indazole SDSbuy 6-Bromo-4-methoxy-1H-indazole6-Bromo-4-methoxy-1H-indazole supplier6-Bromo-4-methoxy-1H-indazole uses6-Bromo-4-methoxy-1H-indazole molecular weightprice of 6-Bromo-4-methoxy-1H-indazole6-Bromo-4-methoxy-1H-indazole chemical name formula of 6-Bromo-4-methoxy-1H-indazole