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CS-W001157 4
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3-Phenyl-5,6,7,8-tetrahydro-imidazo[1,2-a]pyrazine

  • CAS No. 885281-16-3

  • Cat. No. CS-0005439
  • Purity≥97%
  • MDL No.MFCD06738955

*For research and further manufacturing use only, not for direct human use.

3-Phenyl-5,6,7,8-tetrahydro-imidazo[1,2-a]pyrazine|CS-0005439

Structure of 885281-16-3

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General Information

  • CAS No. 885281-16-3
  • Cat. No. CS-0005439
  • Purity ≥97%
  • MDL No. MFCD06738955
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₃N₃
  • Molecular Weight 199.25
  • Synonym(s) 3-Phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine
  • SMILES N12C(C3=CC=CC=C3)=CN=C1CNCC2

Description

3-Phenyl-5,6,7,8-tetrahydro-imidazo[1,2-a]pyrazine is a nitrogen-rich heterocyclic scaffold featuring a fused imidazopyrazine core with a pendant phenyl group. This rigid, electron-deficient framework integrates seamlessly into medicinal chemistry libraries, offering enhanced metabolic stability and favorable binding interactions in target-directed synthesis.

Application

3-Phenyl-5,6,7,8-tetrahydro-imidazo[1,2-a]pyrazine serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to biologically relevant scaffolds. Its saturated imidazopyrazine core exhibits favorable bench stability and compatibility with common functional group transformations. The phenyl substituent enhances π-stacking potential, while the nitrogen-rich framework supports diverse derivatization via electrophilic substitution or reductive amination, facilitating rapid analog generation for target-directed synthesis.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H320-H335
Precautionary Statements : P261-P280-P302+P352

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Computational Chemistry Data

  • TPSA   29.85
  • LogP   1.6533
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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