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CS-W001157 4
Total: USD 88.00

5-Bromo-3-methyl-1H-pyrazolo[3,4-b]pyridine

  • CAS No. 885223-65-4

  • Cat. No. CS-W003801
  • Purity≥98%
  • MDL No.MFCD11846319

*For research and further manufacturing use only, not for direct human use.

5-Bromo-3-methyl-1H-pyrazolo[3,4-b]pyridine|CS-W003801

Structure of 885223-65-4

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General Information

  • CAS No. 885223-65-4
  • Cat. No. CS-W003801
  • Purity ≥98%
  • MDL No. MFCD11846319
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆BrN₃
  • Molecular Weight 212.05
  • Synonym(s) o[3,4-b]pyridine
  • SMILES Brc1cnc2c(c1)c(C)n[nH]2

Description

5-Bromo-3-methyl-1H-pyrazolo[3,4-b]pyridine is a heterocyclic scaffold featuring a bromine substituent at the 5-position and a methyl group at the 3-position, enabling selective functionalization in cross-coupling reactions. This electron-deficient pyrazolopyridine core integrates readily into pharmaceutical intermediates and advanced materials due to its stability and predictable reactivity under standard coupling conditions.

Application

5-Bromo-3-methyl-1H-pyrazolo[3,4-b]pyridine serves as a versatile building block for the synthesis of biologically active heterocycles. Its bromine and methyl groups enable selective functionalization via Pd-catalyzed cross-coupling and electrophilic substitution. The scaffold exhibits good bench stability and compatibility with standard reaction conditions, facilitating efficient access to complex pyrazolopyridine derivatives in medicinal chemistry and materials science applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   41.57
  • LogP   2.02882
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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