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CS-W001157 4
Total: USD 88.00

4-Bromo-7-fluoro-1H-indole

  • CAS No. 883500-66-1

  • Cat. No. CS-W008483
  • Purity≥95%
  • MDL No.MFCD03095318

*For research and further manufacturing use only, not for direct human use.

4-Bromo-7-fluoro-1H-indole|CS-W008483

Structure of 883500-66-1

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General Information

  • CAS No. 883500-66-1
  • Cat. No. CS-W008483
  • Purity ≥95%
  • MDL No. MFCD03095318
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₅BrFN
  • Molecular Weight 214.03
  • Synonym(s) 4-BROMO-7-FLUOROINDOLE
  • SMILES FC1=CC=C(Br)C2=C1NC=C2

Description

4-Bromo-7-fluoro-1H-indole is a halogenated indole scaffold featuring strategic bromo and fluoro substitutions at the 4- and 7-positions, respectively. This electron-deficient heterocycle integrates readily into cross-coupling reactions and serves as a key building block for bioactive molecules in medicinal chemistry and materials science.

Application

4-Bromo-7-fluoro-1H-indole serves as a valuable building block for medicinal chemistry and materials science, enabling direct functionalization at the C4 and C7 positions. Its halogenated indole core facilitates palladium-catalyzed cross-coupling reactions and provides orthogonal reactivity for further diversification. The compound exhibits good bench stability and compatibility with standard synthetic workflows, making it ideal for constructing complex heterocyclic scaffolds in API development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   15.79
  • LogP   3.0695
  • H_Acceptors   0
  • H_Donors   1
  • Rotatable_Bonds   0

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