Lot numbers can be found on the outside label of a product:
4-Azidobutylamine
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CAS No. 88192-20-5
- Cat. No. CS-0028502
- Purity≥95%
- MDL No.MFCD11046232
*For research and further manufacturing use only, not for direct human use.
Structure of 88192-20-5
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General Information
- CAS No. 88192-20-5
- Cat. No. CS-0028502
- Purity ≥95%
- MDL No. MFCD11046232
- Storage 4°C, protect from light
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₄H₁₀N₄
- Molecular Weight 114.15
- Synonym(s) None
- SMILES NCCCCN=[N+]=[N-]
Description
4-Azidobutylamine is a bifunctional reagent featuring a terminal azide group and a primary amine, enabling efficient bioorthogonal conjugation and site-specific labeling in synthetic and biochemical applications.
Application
4-Azidobutylamine serves as a versatile bifunctional building block for bioconjugation and polymer chemistry. The primary amine enables facile coupling via amide or imine formation, while the terminal azide supports efficient copper-catalyzed (CuAAC) or strain-promoted (SPAAC) cycloaddition reactions. Its linear aliphatic spacer provides optimal flexibility and reduced steric hindrance in conjugation workflows, enhancing reaction kinetics and yield. Bench-stable and readily purified by standard chromatographic methods, it functions reliably in peptide modification, probe synthesis, and surface functionalization applications.
Synthesis
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Route1
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24345-72-0 - ~88%
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In-stock
88192-20-5
References
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Srinivasan, Rajavel; Tan, Lay Pheng; Wu, Hao; Yang, Peng-Yu; Kalesh, Karunakaran A.; Yao, Shao Q. Organic and Biomolecular Chemistry, 2009 , vol. 7, # 9 p. 1821 - 1828
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Route2
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110-60-1
- ~62%
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In-stock
88192-20-5
References
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NATIONAL TSING HUA UNIVERSITY Patent: US2011/306668 A1, 2011 ; Location in patent: Page/Page column 23-24 ;
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Route3
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110-60-1
- ~39%
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24345-72-0
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In-stock
88192-20-5
References
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Su, Yuan-Hsiao; Chiang, Li-Wu; Jeng, Kee-Ching; Huang, Ho-Lien; Chen, Jenn-Tzong; Lin, Wuu-Jyh; Huang, Chia-Wen; Yu, Chung-Shan Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 5 p. 1320 - 1324
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Safety Information
Download SDS|
GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Quality Control
Computational Chemistry Data
- TPSA 74.78
- LogP 1.0356
- H_Acceptors 2
- H_Donors 1
- Rotatable_Bonds 4
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