Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

5-Chloro-1H-pyrazole-3-carboxylic acid

  • CAS No. 881668-70-8

  • Cat. No. CS-W003620
  • Purity≥98%
  • MDL No.MFCD09608056

*For research and further manufacturing use only, not for direct human use.

5-Chloro-1H-pyrazole-3-carboxylic acid|CS-W003620

Structure of 881668-70-8

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 881668-70-8
  • Cat. No. CS-W003620
  • Purity ≥98%
  • MDL No. MFCD09608056
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₃ClN₂O₂
  • Molecular Weight 146.53
  • Synonym(s) 5-Chloropyrazole-3-carboxylicacid
  • SMILES OC(=O)c1cc([nH]n1)Cl

Description

5-Chloro-1H-pyrazole-3-carboxylic acid features a chlorinated pyrazole core with a carboxylic acid at the 3-position, enabling direct conjugation in bioactive molecule synthesis. This electron-deficient heterocycle integrates readily into pharmaceutical scaffolds and serves as a key intermediate in medicinal chemistry campaigns targeting kinase inhibitors and antimicrobial agents.

Application

5-Chloro-1H-pyrazole-3-carboxylic acid serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient access to substituted pyrazole scaffolds. Its carboxylic acid functionality facilitates direct coupling reactions, while the 5-chloro substituent provides a handle for palladium-catalyzed cross-coupling transformations. The compound exhibits good bench stability and is compatible with standard purification methods, making it well-suited for use in multi-step syntheses of bioactive heterocycles.

Synthesis

  • Route1

    References

    • BIOLIPOX AB Patent: WO2007/45868 A1, 2007 ; Location in patent: Page/Page column 43 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   65.98
  • LogP   0.7613
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 5-Chloro-1H-pyrazole-3-carboxylic acid sigma5-Chloro-1H-pyrazole-3-carboxylic acid manufacturer5-Chloro-1H-pyrazole-3-carboxylic acid price5-Chloro-1H-pyrazole-3-carboxylic acid structure5-Chloro-1H-pyrazole-3-carboxylic acid SDSbuy 5-Chloro-1H-pyrazole-3-carboxylic acid5-Chloro-1H-pyrazole-3-carboxylic acid supplier5-Chloro-1H-pyrazole-3-carboxylic acid uses5-Chloro-1H-pyrazole-3-carboxylic acid molecular weightprice of 5-Chloro-1H-pyrazole-3-carboxylic acid5-Chloro-1H-pyrazole-3-carboxylic acid chemical name formula of 5-Chloro-1H-pyrazole-3-carboxylic acid
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label