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Structure of 881402-16-0
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This boronate-functionalized pyridine integrates readily into Suzuki-Miyaura coupling reactions under standard conditions, delivering trifluoromethyl-substituted biaryls with high fidelity. The tetramethyl-1,3,2-dioxaborolane moiety ensures excellent stability and ease of handling, while the para-trifluoromethyl group imparts strong electron-withdrawing character, enhancing reactivity in cross-coupling processes.
2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)pyridine serves as a versatile boronate building block in palladium-catalyzed cross-coupling reactions. The tetramethylborolane moiety ensures excellent stability and ease of handling, while the trifluoromethyl group imparts enhanced metabolic stability and lipophilicity. This compound facilitates efficient C–C bond formation under standard Suzuki-Miyaura conditions, enabling rapid access to functionalized heterocycles relevant to medicinal chemistry and materials science.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301
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Precautionary Statements : P264-P270-P330-P405-P501
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Lot numbers can be found on the outside label of a product: