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Structure of 881190-94-9
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5-Chloro-6-fluoro-2,3-dihydro-1H-inden-1-one features a fused bicyclic core with complementary halogen substituents enabling precise tuning of reactivity. The electron-deficient carbonyl group pairs effectively with nucleophiles, while the fluorine and chlorine atoms enhance metabolic stability and modulate electronic distribution. This structure serves as a key scaffold in bioactive molecule synthesis.
5-Chloro-6-fluoro-2,3-dihydro-1H-inden-1-one serves as a versatile synthetic building block for the construction of fluorinated heterocycles and bioactive scaffolds. Its ortho-halogenated indenone core enables efficient palladium-catalyzed cross-coupling reactions and facilitates electrophilic functionalization at the aromatic ring. The molecule exhibits good bench stability and compatibility with common protecting group strategies, making it well-suited for iterative synthesis in medicinal chemistry campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: