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Structure of 88016-31-3
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Methyl 2-(((trifluoromethyl)sulfonyl)oxy)acetate is a bench-stable, moisture-tolerant reagent enabling efficient O-alkylation in synthetic workflows. The trifluoromethylsulfonyl group delivers exceptional leaving-group ability, facilitating clean displacement reactions with nucleophiles. This ester integrates readily into complex molecule assembly where selective ether formation is required.
Methyl 2-(((trifluoromethyl)sulfonyl)oxy)acetate serves as a highly effective trifluoromethanesulfonate (triflate) equivalent for electrophilic triflation and C–H functionalization reactions. Its stability under ambient conditions and compatibility with diverse functional groups enable reliable installation of the trifluoromethylsulfonyl moiety in complex molecule synthesis. The compound facilitates efficient coupling processes, particularly in transition-metal-catalyzed transformations, and functions as a key building block in the construction of fluorinated pharmaceutical intermediates and agrochemical scaffolds.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501
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Lot numbers can be found on the outside label of a product: