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CS-W001157 4
Total: USD 88.00

2-Aminobenzenesulfonic acid

  • CAS No. 88-21-1

  • Cat. No. CS-W016018
  • Purity≥97%
  • MDL No.MFCD00007705

*For research and further manufacturing use only, not for direct human use.

2-Aminobenzenesulfonic acid|CS-W016018

Structure of 88-21-1

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General Information

  • CAS No. 88-21-1
  • Cat. No. CS-W016018
  • Purity ≥97%
  • MDL No. MFCD00007705
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇NO₃S
  • Molecular Weight 173.19
  • Synonym(s) Orthanilic acid; 2-Aminobenzenesulphonic acid
  • SMILES NC1=C(C=CC=C1)S(O)(=O)=O

Description

2-Aminobenzenesulfonic acid features a sulfonic acid group directly attached to the aromatic ring, conferring high water solubility and strong acidity. The ortho-amino functionality enables facile coupling reactions in dye synthesis and pharmaceutical intermediates. This bench-stable compound serves as a key building block for azo dyes, sulfonamide derivatives, and functional polymers.

Application

2-Aminobenzenesulfonic acid serves as a key building block in the synthesis of azo dyes, sulfonamide derivatives, and pharmaceutical intermediates. Its dual functionality—amine and sulfonic acid groups—enables facile coupling reactions and enhances water solubility. The compound exhibits good bench stability and is compatible with standard purification techniques, facilitating its use in multi-step syntheses and scale-up processes.

Synthesis

  • Route1

    References

    • Jagadeesh, Rajenahally V.; Kiran; Bhagat, Pundlik R.; Kumar, S. Senthil; Nithya; Khan, F. Nawaz; Sivakumar Journal of Molecular Catalysis A: Chemical, 2011 , vol. 338, # 1-2 p. 92 - 104
  • Route2
    • Benzothiazole, ≥96%|CS-1269066
      95-16-9
    • ~84%
    • In-stock
      2-Aminobenzenesulfonic acid|CS-W016018
      88-21-1

    References

    • Jagadeesh, Rajenahally V.; Sandhya, Y. Sree; Karthikeyan; Reddy, S. Sudhakar; Reddy, P. Pradeep Kumar; Kumar, M. Viniod; Charan, K. T. Prabhu; Narender; Bhagat Synthetic Communications, 2011 , vol. 41, # 16 p. 2343 - 2349
  • Route3
    • null|null
      100-65-2
    • ~%
    • In-stock
      2-Aminobenzenesulfonic acid|CS-W016018
      88-21-1
    • Phenylsulfamic Acid|CS-0768409
      3345-86-6

    References

    • Ber., , vol. 30, p. 645 - 655 Ber., , vol. 34, p. 228 - 253

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 2585
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   80.39
  • LogP   0.5155
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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