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6-Amino-1-methyl-1,3-dihydro-2H-benzo[d]imidazol-2-one hydrochloride

  • CAS No. 879658-18-1

  • Cat. No. CS-0371181
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

6-Amino-1-methyl-1,3-dihydro-2H-benzo[d]imidazol-2-one hydrochloride|CS-0371181

Structure of 879658-18-1

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General Information

  • CAS No. 879658-18-1
  • Cat. No. CS-0371181
  • Purity ≥95%
  • MDL No. None
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀ClN₃O
  • Molecular Weight 199.64
  • Synonym(s) 6-Amino-1-methyl-2,3-dihydro-1H-1,3-benzodiazol-2-one hydrochloride
  • SMILES O=C1NC2=CC=C(N)C=C2N1C.[H]Cl

Description

6-Amino-1-methyl-1,3-dihydro-2H-benzo[d]imidazol-2-one hydrochloride features a protonated amine and a ketone-bearing heterocycle, enabling direct integration into peptide-coupling workflows. The hydrochloride salt enhances solubility in aqueous and polar organic media, supporting reliable handling under standard bench conditions. This scaffold serves as a rigid, electron-rich building block for bioconjugation and medicinal chemistry applications.

Application

6-Amino-1-methyl-1,3-dihydro-2H-benzo[d]imidazol-2-one hydrochloride serves as a versatile building block for bioactive heterocycles, enabling efficient access to substituted benzimidazoles via standard amine functionalization. The compound exhibits excellent bench stability, facilitates straightforward purification, and demonstrates broad compatibility with common coupling and cyclization protocols in medicinal chemistry workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   63.81
  • LogP   0.8706
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   0

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