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CS-W001157 4
Total: USD 88.00

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-methylpent-4-enoic acid

  • CAS No. 87720-55-6

  • Cat. No. CS-0101044
  • Purity≥98%
  • MDL No.MFCD00237651

*For research and further manufacturing use only, not for direct human use.

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-methylpent-4-enoic acid|CS-0101044

Structure of 87720-55-6

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General Information

  • CAS No. 87720-55-6
  • Cat. No. CS-0101044
  • Purity ≥98%
  • MDL No. MFCD00237651
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₁H₂₁NO₄
  • Molecular Weight 351.40
  • Synonym(s) Fmoc-4,5-dehydro-l-leucine
  • SMILES C=C(C)C[C@H](NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)C(O)=O

Description

This fluorenonyl-methoxycarbonyl-protected amino acid derivative features a chiral (S)-configuration and a terminal alkene, enabling selective conjugation in peptide synthesis. The Fmoc group ensures stability during handling and facilitates efficient deprotection under mild basic conditions. This scaffold integrates seamlessly into solid-phase workflows for the construction of complex peptides and peptidomimetics.

Synthesis

  • Route1
    • null|null
      28920-43-6
    • L-Methallylglycine|CS-0040778
      87392-13-0
    • ~90%
    • In-stock
      (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-methylpent-4-enoic acid|CS-0101044
      87720-55-6

    References

    • Hardy, Paul M.; Sheppard, Paul W. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 4 p. 723 - 729

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   3.9445
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   6

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