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CS-W001157 4
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1-(Triisopropylsilyl)-1H-pyrrole

  • CAS No. 87630-35-1

  • Cat. No. CS-0132446
  • Purity≥97%
  • MDL No.MFCD00054932

*For research and further manufacturing use only, not for direct human use.

1-(Triisopropylsilyl)-1H-pyrrole|CS-0132446

Structure of 87630-35-1

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General Information

  • CAS No. 87630-35-1
  • Cat. No. CS-0132446
  • Purity ≥97%
  • MDL No. MFCD00054932
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₂₅NSi
  • Molecular Weight 223.43
  • Synonym(s) 1-(tripropan-2-ylsilyl)-1H-pyrrole
  • SMILES CC([Si](N1C=CC=C1)(C(C)C)C(C)C)C

Description

1-(Triisopropylsilyl)pyrrole (TISP), a heterocyclic building block, is a pyrrole derivative. TISP has been reported to generate pyrrolic cation radicals during cyclovoltammetric studies, via electroreduction. It participates in various electrophilic substitution reactions specifically at -position, via reaction with various electrophilic reagents (Br+, I+,NO2+,etc).1-(Triisopropylsilyl)pyrrole may be employed as reagent in perfluoroalkylation and Vilsmeier formylation reactions. It may be used in the preparation of:ethyl 2-(2,4-dinitrophenylhydrazono]-3-[ 1-(triisopropylsily1)-pyrrol-2-yflpropanoateheterocyclic base, 3-nitropyrrole3-nitropyrrole, required for the synthesis of 1 -(2-deoxy--D-ribofuranosyl)-3-nitropyrrole

Synthesis

  • Route1
    • null|null
      130408-79-6
    • ~73%
    • In-stock
      1-(Triisopropylsilyl)-1H-pyrrole|CS-0132446
      87630-35-1

    References

    • Koike, Takeshi; Shinohara, Yoshifumi; Nishimura, Takeshi; Hagiwara, Masanori; Tobinaga, Seisho; Takeuchi, Naoki Heterocycles, 2000 , vol. 53, # 6 p. 1351 - 1359
  • Route2

    References

    • Organic Letters, , vol. 15, # 12 p. 2954 - 2957
  • Route3
    • null|null
      13154-24-0
    • null|null
      16199-06-7
    • ~%
    • In-stock
      1-(Triisopropylsilyl)-1H-pyrrole|CS-0132446
      87630-35-1

    References

    • Journal of the American Chemical Society, , vol. 112, # 6 p. 2439 - 2440 Journal of Physical Chemistry, , vol. 95, # 24 p. 10158 - 10164

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302+H332-H319
Precautionary Statements : P261-P264-P270-P271-P280-P304+P340-P330-P501

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Computational Chemistry Data

  • TPSA   4.93
  • LogP   4.5117
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   4

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