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CS-W001157 4
Total: USD 88.00

Biotin-PEG3-azide

  • CAS No. 875770-34-6

  • Cat. No. CS-0105250
  • Purity≥97%
  • MDL No.MFCD20134145

*For research and further manufacturing use only, not for direct human use.

Biotin-PEG3-azide|CS-0105250

Structure of 875770-34-6

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General Information

  • CAS No. 875770-34-6
  • Cat. No. CS-0105250
  • Purity ≥97%
  • MDL No. MFCD20134145
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₈H₃₂N₆O₅S
  • Molecular Weight 444.55
  • Synonym(s) None
  • SMILES O=C(NCCOCCOCCOCCN=[N+]=[N-])CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O

Description

Azide-PEG3-biotin conjugate has been used for the detection of a cellular alkyne cholesterol analog via click chemistry using fluorescence microscopy after incubation with a fluorescent streptavidin-conjugate. It has also been used to prepare a novel multifunctional benzophenone linker that can be used for pull-down assays, photoaffinity labeling and double-click stapling techniques.

Synthesis

  • Route1

    References

    • THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL; KOHN, Harold, L.; PARK, Ki Duk Patent: WO2010/14236 A2, 2010 ; Location in patent: Page/Page column 35 ;
  • Route2

    References

    • Tantama, Mathew; Lin, Wan-Chen; Licht, Stuart Journal of the American Chemical Society, 2008 , vol. 130, # 47 p. 15766 - 15767
  • Route3

    References

    • Yun, Wang; Shougang, Hu; Fast, Walter Journal of the American Chemical Society, 2009 , vol. 131, # 42 p. 15096 - 15097

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   146.68
  • LogP   1.1885
  • H_Acceptors   7
  • H_Donors   3
  • Rotatable_Bonds   17

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