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CS-W001157 4
Total: USD 88.00

2-Hydroxy-4-methylthiazole-5-carboxylic acid

  • CAS No. 875237-46-0

  • Cat. No. CS-0187813
  • Purity≥97%
  • MDL No.None
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Hydroxy-4-methylthiazole-5-carboxylic acid|CS-0187813

Structure of 875237-46-0

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Description

2-Hydroxy-4-methylthiazole-5-carboxylic acid features a fused heterocyclic core with strategically positioned hydroxyl, methyl, and carboxylic acid groups enabling versatile conjugation. This bench-stable scaffold integrates readily into synthetic workflows requiring polar, electron-deficient motifs for medicinal chemistry or materials applications.

Application

2-Hydroxy-4-methylthiazole-5-carboxylic acid serves as a versatile heterocyclic building block for medicinal chemistry and materials science applications. Its dual functionality—phenolic hydroxyl and carboxylic acid—enables facile derivatization via amidation, esterification, or metal-catalyzed coupling reactions. The molecule exhibits good bench stability and facilitates purification through crystallization or standard chromatographic methods, supporting its use in scalable synthesis of thiazole-based pharmacophores and functionalized polymers.

General Information

  • CAS No. 875237-46-0
  • Cat. No. CS-0187813
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₅NO₃S
  • Molecular Weight 159.16
  • Synonym(s) 5-thiazolecarboxylic acid, 2-hydroxy-4-methyl-
  • SMILES CC1=C(C(=O)O)SC(=N1)O

Computational Chemistry Data

  • TPSA   70.42
  • LogP   0.85532
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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