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CS-W001157 4
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2-(3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate

  • CAS No. 873798-09-5

  • Cat. No. CS-W011999
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-(3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate|CS-W011999

Structure of 873798-09-5

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General Information

  • CAS No. 873798-09-5
  • Cat. No. CS-W011999
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₅BF₄N₆O
  • Molecular Weight 322.07
  • Synonym(s) O-(7-Azabenzotriazole-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate
  • SMILES CN(/C(ON1C2=C(N=N1)C=CC=N2)=[N+](C)\C)C.F[B-](F)(F)F

Description

Cresol Red sodium salt acts as a constituent of polymerase chain reaction reagent systems. It is useful as a pH indicator with color changes with pH 0.2 - pH 1.8 and pH 7.1 - 8.8. Further, it plays an important role in molecular biology reactions in place of other loading dyes.

Application

2-(3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate serves as a robust amidation reagent, enabling efficient amide bond formation under mild conditions. Its triazolopyridine-activated urea structure provides enhanced electrophilicity and stability compared to conventional HBTU-type reagents. The tetrafluoroborate counterion ensures good solubility in organic solvents and facilitates clean reaction work-up. This reagent functions effectively in peptide synthesis and functionalization of complex heterocycles, offering reliable yields and high purity with minimal racemization.

Safety Information

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GHS Pictogram :
GHS No : GHS02,GHS07
Signal Word : Danger
UN#: 1325
Class : 4.1
Packing Group : Ⅱ
Hazard Statements : H228-H315-H319-H335
Precautionary Statements : P210-P240-P261-P264-P271-P280-P302+P352-P304+P340-P362-P370+P378-P501

Quality Control

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Computational Chemistry Data

  • TPSA   59.08
  • LogP   0.7446
  • H_Acceptors   5
  • H_Donors   0
  • Rotatable_Bonds   1

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