5-Bromo-N-methylpyridin-3-amine

Name: 5-Bromo-N-methylpyridin-3-amine
Brand: ChemScene
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CAS No. 873383-06-3
Cat. No. CS-0151021
Purity≥95%
MDL No.MFCD13190575

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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5-Bromo-N-methylpyridin-3-amine|CS-0151021

Structure of 873383-06-3

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Description

5-Bromo-N-methylpyridin-3-amine features a brominated pyridine core with a methylated amine substituent at the 3-position, enabling direct coupling in cross-coupling reactions. The electron-deficient ring and pendant N-methyl group facilitate efficient incorporation into bioactive scaffolds, offering enhanced metabolic stability and solubility under standard conditions.

Application

5-Bromo-N-methylpyridin-3-amine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its bromine functional group. The N-methylpyridin-3-amine core provides a stable, electron-rich heterocyclic scaffold with favorable solubility and bench stability, facilitating efficient synthesis of complex molecules for drug discovery applications.

General Information

CAS No. 873383-06-3
Cat. No. CS-0151021
Purity ≥95%
MDL No. MFCD13190575
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₇BrN₂
Molecular Weight 187.04
Synonym(s) (5-BROMO-PYRIDIN-3-YL)-METHYL-AMINE
SMILES CNC1=CN=CC(=C1)Br

Computational Chemistry Data

TPSA 24.92
LogP 1.8858
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H320-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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5-Bromo-N-methylpyridin-3-amine

CAS No. 873383-06-3

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