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CS-W001157 4
Total: USD 88.00

(3R)-3-Iodooxolane

  • CAS No. 873063-62-8

  • Cat. No. CS-0055199
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(3R)-3-Iodooxolane|CS-0055199

Structure of 873063-62-8

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General Information

  • CAS No. 873063-62-8
  • Cat. No. CS-0055199
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₇IO
  • Molecular Weight 198.00
  • Synonym(s) (R)-3-Iodo-tetrahydrofuran
  • SMILES I[C@H]1COCC1

Description

(3R)-3-Iodooxolane is a chiral oxolane derivative featuring a stereodefined iodine substituent at the 3-position, enabling selective transformations in asymmetric synthesis. This bench-stable, moisture-tolerant building block integrates readily into cascade reactions and serves as a key intermediate for complex heterocyclic systems.

Application

(3R)-3-Iodooxolane serves as a stereodefined building block for the synthesis of biologically relevant heterocycles and carbohydrate mimetics. The iodide functionality enables efficient palladium-catalyzed cross-coupling reactions, while the oxolane ring provides structural rigidity and favorable solubility. Its bench-stable nature and compatibility with common protecting group strategies facilitate straightforward incorporation into complex molecular architectures.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   9.23
  • LogP   1.2103
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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