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CS-W001157 4
Total: USD 88.00

3-Formylphenylboronic acid

  • CAS No. 87199-16-4

  • Cat. No. CS-W002464
  • Purity≥96%
  • MDL No.MFCD00161356

*For research and further manufacturing use only, not for direct human use.

3-Formylphenylboronic acid|CS-W002464

Structure of 87199-16-4

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General Information

  • CAS No. 87199-16-4
  • Cat. No. CS-W002464
  • Purity ≥96%
  • MDL No. MFCD00161356
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₇BO₃
  • Molecular Weight 149.94
  • Synonym(s) None
  • SMILES O=CC1=CC(B(O)O)=CC=C1

Application

3-Formylphenylboronic acid serves as a versatile building block in Suzuki-Miyaura coupling reactions, enabling efficient construction of biaryl scaffolds under mild conditions. The ortho-formyl group provides a handle for further functionalization via condensation or oxidation reactions, while the boronic acid moiety offers excellent bench stability and compatibility with diverse reaction partners. Its dual functionality facilitates access to complex aromatic systems commonly found in pharmaceutical intermediates and advanced materials.

Synthesis

  • Route1
    • null|null
      540777-53-5
    • null|null
      121-43-7
    • ~90%
    • In-stock
      3-Formylphenylboronic acid|CS-W002464
      87199-16-4

    References

    • TEIJIN LIMITED Patent: EP1460059 A1, 2004 ; Location in patent: Page 9 ;
  • Route2
    • null|null
      68578-52-9
    • ~91%
    • In-stock
      3-Formylphenylboronic acid|CS-W002464
      87199-16-4

    References

    • Meudt, Andreas; Scherer, Stefan; Vollmueller, Frank; Erbes, Michael Patent: US2004/49050 A1, 2004 ;
  • Route3

    References

    • Chemical Communications, , vol. 46, # 15 p. 2677 - 2679

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   57.53
  • LogP   -0.8211
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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