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CS-W001157 4
Total: USD 88.00

3-Isopropoxy-azetidine

  • CAS No. 871791-79-6

  • Cat. No. CS-0005430
  • Purity≥98%
  • MDL No.MFCD09997788

*For research and further manufacturing use only, not for direct human use.

3-Isopropoxy-azetidine|CS-0005430

Structure of 871791-79-6

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General Information

  • CAS No. 871791-79-6
  • Cat. No. CS-0005430
  • Purity ≥98%
  • MDL No. MFCD09997788
  • Storage -20°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₃NO
  • Molecular Weight 115.17
  • Synonym(s) 3-Isopropoxyazetidine
  • SMILES CC(C)OC1CNC1

Description

3-Isopropoxy-azetidine features a strained four-membered azetidine ring bearing a pendant isopropoxy group, delivering enhanced nucleophilicity and solubility in polar organic media. This bench-stable heterocycle integrates readily into synthetic routes requiring constrained nitrogen scaffolds with tailored lipophilicity, enabling efficient incorporation into bioactive molecule frameworks under standard conditions.

Application

3-Isopropoxyazetidine serves as a valuable building block in medicinal chemistry, enabling the construction of bioactive heterocycles through reliable ring-opening and coupling reactions. Its strained azetidine core enhances reactivity in nucleophilic substitutions, while the isopropoxy group provides steric bulk and modulates solubility. The compound exhibits good bench stability and compatibility with diverse functional groups, facilitating straightforward purification and integration into complex molecular architectures.

Safety Information

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Computational Chemistry Data

  • TPSA   21.26
  • LogP   0.3832
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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