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Methyl 4-chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylate

  • CAS No. 871583-23-2

  • Cat. No. CS-D0068
  • Purity≥95%
  • MDL No.MFCD09839319

*For research and further manufacturing use only, not for direct human use.

Methyl 4-chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylate|CS-D0068

Structure of 871583-23-2

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General Information

  • CAS No. 871583-23-2
  • Cat. No. CS-D0068
  • Purity ≥95%
  • MDL No. MFCD09839319
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₇ClN₂O₂
  • Molecular Weight 210.62
  • Synonym(s) Methyl 4-chloro-7-azaindole-2-carboxylate
  • SMILES O=C(OC)C1=CC2=C(Cl)C=CN=C2N1

Description

Methyl 4-chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylate is a bench-stable heterocyclic ester featuring a chlorinated pyrrolopyridine core. This electron-deficient scaffold integrates readily into cross-coupling reactions and serves as a key building block for bioactive nitrogen-containing compounds in medicinal chemistry.

Application

Methyl 4-chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylate serves as a versatile heterocyclic building block for medicinal chemistry and process development. The chloro substituent at the 4-position enables palladium-catalyzed cross-coupling reactions, while the ester functionality supports derivatization via hydrolysis or reduction. Its bench-stable nature and compatibility with standard reaction conditions facilitate efficient synthesis of complex scaffolds in drug discovery workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   54.98
  • LogP   2.0029
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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