2,3-Dihydrofuro[2,3-b]pyridin-3-amine

Name: 2,3-Dihydrofuro[2,3-b]pyridin-3-amine
Brand: ChemScene
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CAS No. 870061-94-2
Cat. No. CS-B1356
Purity≥90%
MDL No.MFCD13190275

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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2,3-Dihydrofuro[2,3-b]pyridin-3-amine|CS-B1356

Structure of 870061-94-2

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General Information

CAS No. 870061-94-2
Cat. No. CS-B1356
Purity ≥90%
MDL No. MFCD13190275
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₈N₂O
Molecular Weight None
Synonym(s) None
SMILES NC1COC2=NC=CC=C21

Description

This dihydrofuro[2,3-b]pyridin-3-amine features a fused heterocyclic scaffold integrating a pyridine ring with a dihydrofuran moiety, providing a rigid, electron-rich platform for medicinal chemistry applications. The amine functionality enables direct derivatization, while the scaffold exhibits favorable solubility and stability under standard handling conditions.

Application

2,3-Dihydrofuro[2,3-b]pyridin-3-amine serves as a versatile heterocyclic building block for medicinal chemistry and synthetic organic applications. Its fused furan-pyridine core provides structural rigidity and favorable electronic properties, enabling efficient functionalization at the amine site. The compound exhibits good bench stability and compatibility with standard coupling reactions, facilitating incorporation into complex molecular architectures. It functions as a key scaffold in the synthesis of bioactive molecules, particularly those requiring extended π-systems and hydrogen-bonding capability.

Safety Information

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GHS Pictogram :	GHS No : GHS05,GHS07
Signal Word : Danger	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H318-H335
Precautionary Statements : P260-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P305+P351+P338-P310-P312-P330-P332+P313-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 48.14
LogP 0.4738
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 0

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Building Blocks Skeleton Aliphatic heterocycle compounds Tetrahydrofuran compounds

Key Words

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2,3-Dihydrofuro[2,3-b]pyridin-3-amine

CAS No. 870061-94-2

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