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CS-W001157 4
Total: USD 88.00

Violuric acid

  • CAS No. 87-39-8

  • Cat. No. CS-0149651
  • Purity≥97%
  • MDL No.MFCD00006032

*For research and further manufacturing use only, not for direct human use.

Violuric acid|CS-0149651

Structure of 87-39-8

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General Information

  • CAS No. 87-39-8
  • Cat. No. CS-0149651
  • Purity ≥97%
  • MDL No. MFCD00006032
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₃N₃O₄
  • Molecular Weight 157.08
  • Synonym(s) None
  • SMILES ON=C1C(NC(NC1=O)=O)=O

Description

Violuric acid features a fused pyrimidine-dione core with adjacent carbonyl and amide functionalities, enabling direct integration into heterocyclic synthesis. This bench-stable compound serves as a key scaffold for medicinal chemistry campaigns targeting kinase inhibitors and antiviral agents.

Application

Violuric acid serves as a versatile building block in heterocyclic synthesis, particularly for constructing pyrimidine and purine scaffolds. Its malonamide functionality enables facile condensation reactions with carbonyl compounds and amine derivatives under mild conditions. The compound exhibits good bench stability and facilitates efficient purification via crystallization, making it well-suited for iterative synthetic sequences in medicinal chemistry and process development workflows.

Synthesis

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      Violuric acid|CS-0149651
      87-39-8

    References

    • Proceedings of the National Academy of Sciences of the United States of America, , vol. 18, p. 490,494
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      Violuric acid|CS-0149651
      87-39-8

    References

    • Chemische Berichte, , vol. 16, p. 1134 Chemische Berichte, , vol. 32, p. 1734
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      Violuric acid|CS-0149651
      87-39-8

    References

    • Justus Liebigs Annalen der Chemie, , vol. 127, p. 230 Justus Liebigs Annalen der Chemie, , vol. 130, p. 131

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   107.86
  • LogP   -1.8174
  • H_Acceptors   5
  • H_Donors   3
  • Rotatable_Bonds   0

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