4-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)pyridine

Name: 4-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)pyridine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 869901-52-0
Cat. No. CS-0175750
Purity≥98%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)pyridine|CS-0175750

Structure of 869901-52-0

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 869901-52-0
Cat. No. CS-0175750
Purity ≥98%
MDL No. None
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₁₄BNO₂
Molecular Weight 191.03
Synonym(s) Pyridine-4-boronic acid, neopentyl ester
SMILES CC1(COB(OC1)C2=CC=NC=C2)C

Description

4-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)pyridine features a boronate ester group integrated with a pyridine heterocycle, enabling efficient cross-coupling reactions under mild conditions. The dimethyl-substituted dioxaborinane moiety enhances stability and moisture tolerance, while the electron-deficient pyridine ring facilitates selective functionalization in complex molecular architectures. This reagent streamlines the construction of biaryl systems in medicinal chemistry and materials science applications.

Application

4-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)pyridine serves as a stable, bench-ready boronate building block for Suzuki-Miyaura cross-coupling reactions. Its sterically protected dioxaborinane moiety enhances air and moisture stability, enabling reliable coupling with aryl, heteroaryl, and vinyl halides. The pyridine core provides a versatile scaffold for constructing biologically relevant heterocycles, with excellent functional group tolerance and straightforward purification.

Synthesis

Route1
- In-stock
  
  1692-15-5
- 126-30-7
- ~99%
- In-stock
  
  869901-52-0
References
- Maki, Toshikatsu; Ishihara, Kazuaki; Yamamoto, Hisashi Organic Letters, 2005 , vol. 7, # 22 p. 5043 - 5046 Title/Abstract Full Text View citing articles Show Details Maki, Toshikatsu; Ishihara, Kazuaki; Yamamoto, Hisashi Tetrahedron, 2007 , vol. 63, # 35 p. 8645 - 8657

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 31.35
LogP 0.8498
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 1

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

869901-52-0 sigma869901-52-0 manufacturer869901-52-0 price869901-52-0 structure869901-52-0 SDSbuy 869901-52-0869901-52-0 supplier869901-52-0 uses869901-52-0 molecular weightprice of 869901-52-0869901-52-0 chemical name formula of 869901-52-0

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

4-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)pyridine

CAS No. 869901-52-0

Recommended Products