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Structure of 869500-07-2
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1-Bromo-2-iodo-3-methylbenzene features a methyl group flanked by bromo and iodo substituents on a benzene ring, enabling precise functionalization in cross-coupling reactions. The ortho-halogen arrangement supports sequential metalation and palladium-catalyzed transformations, while the methyl group enhances solubility and stability under standard conditions.
1-Bromo-2-iodo-3-methylbenzene serves as a versatile diaryl building block for palladium-catalyzed cross-coupling reactions. The orthogonal halogen reactivity enables sequential functionalization—bromine participates in Suzuki, Stille, or Negishi couplings, while the iodine moiety offers high reactivity in Buchwald–Hartwig amination or Sonogashira coupling. Bench-stable and readily purified by flash chromatography, it facilitates efficient access to substituted biaryl and heterocyclic scaffolds common in medicinal chemistry and materials science.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: