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Structure of 867333-29-7
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2-Chloro-5-nitrobenzeneboronic acid features a boronate group flanked by electron-withdrawing chlorine and nitro substituents, enhancing its reactivity in Suzuki-Miyaura couplings. The para-chloro and meta-nitro arrangement imparts stability under standard conditions while enabling selective functionalization in complex molecular architectures. This compound serves as a key building block for bioactive heterocycles and advanced materials synthesis.
2-Chloro-5-nitrobenzeneboronic acid serves as a versatile building block in transition-metal-catalyzed cross-coupling reactions, enabling efficient C–C bond formation under mild conditions. The ortho-chloro and para-nitro substituents provide orthogonal reactivity for downstream functionalization, while the boronic acid group offers excellent bench stability and compatibility with standard Suzuki-Miyaura coupling protocols. Its predictable regiochemistry and high functional group tolerance make it ideal for constructing complex aryl scaffolds in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: