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Structure of 864266-10-4
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Tert-butyl (4-bromo-2-chlorobenzyl)carbamate features a benzyl scaffold bearing bromo and chloro substituents at the para- and ortho-positions, respectively, enabling selective functionalization in cross-coupling reactions. The tert-butyl carbamate group provides robust protection for primary amines, offering stability under diverse reaction conditions while permitting straightforward deprotection with trifluoroacetic acid. This combination supports efficient synthesis of complex amine-containing architectures in medicinal chemistry and materials science.
Tert-butyl (4-bromo-2-chlorobenzyl)carbamate serves as a versatile building block in medicinal chemistry, enabling the introduction of a bromo- and chloro-substituted benzylamine moiety. Its tert-butyl carbamate group provides robust protection for primary amines, offering excellent bench stability and ease of removal under mild acidic conditions. The molecule exhibits high functional group tolerance and facilitates efficient coupling reactions, making it ideal for constructing complex heterocyclic scaffolds and API intermediates in multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: