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CS-W001157 4
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2-(5-Bromo-2-thienyl)ethylamine

  • CAS No. 86423-64-5

  • Cat. No. CS-0157331
  • Purity≥97%
  • MDL No.MFCD04114538

*For research and further manufacturing use only, not for direct human use.

2-(5-Bromo-2-thienyl)ethylamine|CS-0157331

Structure of 86423-64-5

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General Information

  • CAS No. 86423-64-5
  • Cat. No. CS-0157331
  • Purity ≥97%
  • MDL No. MFCD04114538
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₈BrNS
  • Molecular Weight None
  • Synonym(s) 2-(5-Bromothiophen-2-yl)ethan-1-amine
  • SMILES C1=C(CCN)SC(=C1)Br

Description

2-(5-Bromo-2-thienyl)ethylamine features a brominated thiophene ring linked to an ethylamine chain, enabling direct incorporation into bioactive molecule scaffolds. The electron-deficient thiophene moiety enhances reactivity in cross-coupling processes, while the primary amine facilitates conjugation and derivatization under standard conditions. This compound serves as a key building block for pharmaceutical intermediates and functional materials requiring halogenated heterocyclic motifs.

Application

2-(5-Bromo-2-thienyl)ethylamine serves as a versatile building block for the synthesis of thienyl-containing pharmaceutical intermediates and functional materials. Its brominated thiophene moiety enables efficient palladium-catalyzed cross-coupling reactions, while the primary amine facilitates conjugation, derivatization, or incorporation into heterocyclic frameworks. The compound exhibits good bench stability and compatibility with standard purification techniques, making it well-suited for iterative synthetic workflows in medicinal chemistry and process development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   2.0118
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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