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CS-W001157 4
Total: USD 88.00

Efinaconazole analogue-1

  • CAS No. 86386-77-8

  • Cat. No. CS-0460244
  • Purity≥98%
  • MDL No.MFCD13184268

*For research and further manufacturing use only, not for direct human use.

Efinaconazole analogue-1|CS-0460244

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General Information

  • CAS No. 86386-77-8
  • Cat. No. CS-0460244
  • Purity ≥98%
  • MDL No. MFCD13184268
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₃F₂N₃O₄S
  • Molecular Weight 333.31
  • Synonym(s) None
  • SMILES O=S(O)(C)=O.FC1=CC=C(C2(CN3N=CN=C3)OC2)C(F)=C1

Description

Efinaconazole analogue-1 features a modified triazole core with enhanced lipophilicity, enabling improved penetration through keratin-rich tissues. This derivative maintains the antifungal activity profile of efinaconazole while offering superior stability under ambient conditions and compatibility with topical formulation matrices.

Application

Efinaconazole analogue-1 serves as a well-defined triazole-based scaffold for probing antifungal activity and structure–activity relationships in azole-class compounds. Its stable triazole core enables consistent reactivity in downstream functionalization, while its aryl-substituted side chain enhances metabolic stability and solubility—key attributes for medicinal chemistry optimization. Functions effectively as a building block in targeted synthesis of conazoles and related heterocyclic systems.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   97.61
  • LogP   0.986
  • H_Acceptors   6
  • H_Donors   1
  • Rotatable_Bonds   3

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