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cis-5-Amino-2-Boc-hexahydro-cyclopenta[c]pyrrole

  • CAS No. 863600-81-1

  • Cat. No. CS-0049669
  • Molecule weight226.32
  • Purity≥97%
  • MDL No.MFCD29056567

*For research and further manufacturing use only, not for direct human use.

cis-5-Amino-2-Boc-hexahydro-cyclopenta[c]pyrrole|CS-0049669

Structure of 863600-81-1

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General Information

  • CAS No. 863600-81-1
  • Cat. No. CS-0049669
  • Purity ≥97%
  • MDL No. MFCD29056567
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₂N₂O₂
  • Molecular Weight 226.32
  • Synonym(s) None
  • SMILES C(OC(C)(C)C)(=O)N1C[C@]2([C@@](C1)(C[C@@H](N)C2)[H])[H]

Description

cis-5-Amino-2-Boc-hexahydro-cyclopenta[c]pyrrole is a stereochemically defined, bench-stable heterocyclic scaffold featuring a protected primary amine and a fused cyclopentane-pyrrolidine core. This configuration enables direct incorporation into peptidomimetic sequences and complex alkaloid architectures, offering enhanced conformational rigidity for targeted molecular design.

Application

cis-5-Amino-2-Boc-hexahydro-cyclopenta[c]pyrrole serves as a versatile, bench-stable building block for the synthesis of nitrogen-containing heterocycles and bioactive scaffolds. The protected amine and rigid cis-configured cyclopentapyrrolidine core enable selective functionalization, compatibility with standard coupling reactions, and efficient access to complex cyclic architectures common in medicinal chemistry.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   55.56
  • LogP   1.5906
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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