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Structure of 863111-55-1
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1-Iodo-2-methyl-3-(trifluoromethyl)benzene features a trifluoromethyl group that imparts enhanced electron-withdrawal and metabolic stability, while the iodine atom enables efficient cross-coupling reactions. This aryl halide integrates readily into complex molecular architectures under standard conditions.
1-Iodo-2-methyl-3-(trifluoromethyl)benzene serves as a versatile aryl halide building block in cross-coupling reactions, enabling efficient construction of biaryl scaffolds under palladium catalysis. The trifluoromethyl group imparts enhanced metabolic stability and lipophilicity, while the iodine functionality ensures high reactivity in Suzuki, Stille, and Negishi couplings. Bench-stable and readily purified by flash chromatography, it functions effectively in late-stage functionalization workflows and the synthesis of pharmaceutically relevant heterocycles.
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GHS Pictogram :
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GHS No : GHS02,GHS05
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Signal Word : Danger
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UN#: 1993
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Class : 3
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Packing Group : Ⅲ
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Hazard Statements : H226-H290-H314
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Precautionary Statements : P210-P233-P234-P240-P241-P242-P243-P260-P264-P280-P301+P330+P331-P304+P340-P363-P370+P378-P390-P405-P406-P501
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Lot numbers can be found on the outside label of a product: