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CS-W001157 4
Total: USD 88.00

(2S)-4-(benzyloxy)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-4-oxobutanoic acid

  • CAS No. 86060-84-6

  • Cat. No. CS-W002301
  • Purity≥97%
  • MDL No.MFCD00065630

*For research and further manufacturing use only, not for direct human use.

(2S)-4-(benzyloxy)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-4-oxobutanoic acid|CS-W002301

Structure of 86060-84-6

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General Information

  • CAS No. 86060-84-6
  • Cat. No. CS-W002301
  • Purity ≥97%
  • MDL No. MFCD00065630
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₆H₂₃NO₆
  • Molecular Weight 445.46
  • Synonym(s) None
  • SMILES O=C(O)[C@@H](NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)CC(OCC4=CC=CC=C4)=O

Description

This fluorenylmethoxycarbonyl-protected amino acid derivative features a benzyloxy-substituted side chain and a reactive β-ketoacid functionality, enabling direct incorporation into peptide synthesis workflows. The orthogonal protection strategy facilitates selective deprotection and efficient coupling under standard conditions.

Application

(2S)-4-(Benzyloxy)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-4-oxobutanoic acid serves as a versatile chiral building block for the synthesis of β-amino acid derivatives and peptidomimetics. The fluorenylmethyloxycarbonyl (Fmoc) group enables efficient N-terminal protection in solid-phase peptide synthesis, while the benzyloxy and ketone functionalities offer orthogonal handles for downstream functionalization. Bench-stable and amenable to standard purification methods, it facilitates reliable access to complex scaffolds in medicinal chemistry workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315
Precautionary Statements : P264-P280-P302+P352-P332+P313-P362+P364

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Computational Chemistry Data

  • TPSA   101.93
  • LogP   4.1118
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   8

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